Microscopic and immunohistochemical researches in preneoplastic and tumor lesions of the cervix uterus
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چکیده
This retrospective study refers to the evolution rate of cervical lesions diagnosed from cervical biopsies, respectively the endocervical scrape collected from 2001 to 2008 and found its place as an introduction to a further complex study. In this period of 8 years, in our laboratory were processed a total of 1387 biopsies and endocervical scrape. All histopathological diagnoses can be classified into four categories of injury: inflammation, cervical intraepithelial neoplasia, squamos cervical carcinoma, cervical adenocarcinoma.
منابع مشابه
Significance of immunohistochemical expression of p16INK4a in the differentiation of inflammatory and preneoplastic cervical lesions.
INTRODUCTION Most studies point at the main role of humanpapilloma virus (HPV) in the development of dysplasia and cervical cancer. Due to the low specificity and sensitivity of morphological diagnostic methods it is necessary to find an adequate marker which would be introduced in the screening program for cervical cancer. Most research suggests that p16INK4a is a specific and sensitive marker...
متن کامل[Immunohistochemical expression of p16 and herpes simplex virus type 2 in squamous intraepithelial lesions and cervical cancer].
PURPOSE to demonstrate the expression of biomarkers, detected by immunohistochemical techniques in healthy tissues, as well as in preneoplastic and neoplastic lesions of the uterine cervix. METHODS in order to evaluate the immunohistochemical reactivity of tissues from the uterine cervix to p16 and to type 2 herpes simplex virus (HSV-2), 187 samples of low-grade intraepithelial lesions (LG-IE...
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INTRODUCTION High-risk human papilloma viruses play a main role in the development of cervical dysplasias and carcinomas. p16INK4a can be considered as a surrogate marker of active high-risk human papillomaviruses infection in dysplastic and neoplastic cells of the cervix. This study was aimed at determining the presence and level of pl6INK4a expression in inflammatory, preneoplastic and neopla...
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The aim of this study represents the confirmation of the utility of cytologic investigation in the screening of the preneoplastic and neoplatic lesions of the uterine cervix,comparing the cytologic results with the histolgic diagnosis of the resected specimens.
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